This pick was released to clients on November 10, 2025 at 11:50AM ET.
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Santa Clara at Xavier

November 10, 2025
img8:30 PM Eastern

Xavier has an entirely new roster and a new coach, Richard Pitino, who comes over from New Mexico, where he led the Lobos to the NCAA Tournament on multiple occasions. Pitino was able to bring in some talented shooters among the transfers, including All Wright (yes, that's his name), Malik Messina-Moore, and Isaiah Walker. Messina-Moore led the Musketeers with 17 points in their 74-69 win over Le Moyne on Thursday when they shot 52 percent from 3-point distance. Santa Clara is replacing all five starters and has nearly 70 points per game this season. The Broncos do have wins over Humboldt State and McNeese State to start the season. The Broncos lost five of their last six as underdogs in 2024-24, and they lost their previous five Monday road games. Xavier has won 10 in a row as a favorite. Take Xavier on the moneyline.

1 unit on Xavier -175 (moneyline) (risk 1 to return 1.57)
Result:
LOSS
Final
1H
2H
F
Santa Clara Broncos img
20
48
87
Xavier Musketeers
20
48
68
consensus consensus
odds odds
 
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