The St. Louis Billikens have had a great season, and it would be special to knock off the #1 seed Michigan. St. Louis has not played a very strong schedule. The Billikens' toughest out-of-conference game has been a 1-point win over Santa Clara. St. Louis has the lowest opponent field-goal percentage in the tournament at 38%. Michigan has posted a 32-3 record, with losses to Wisconsin, Duke, and Purdue. Michigan has beaten every good team it faced outside the conference by 20 or more points. I think Michigan is by far the toughest game of the year for St. Louis, and I expect Michigan to come away with another 20+ point win. Make the play on Michigan.
This Pro Pick was released to clients on March 21, 2026 at 9:58AM ET.
Saint Louis vs. Michigan
March 21, 2026
1 unit on Michigan -12.5 (-103) (risk 1 to return 1.97)
Result:
WIN
WIN
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