Michigan State at Butler

These teams are certainly of high caliber, but also unlikely Final Four participants. Butler is a longstanding powerful mid-major, and has surprised a lot of people making their run here. Michigan State has been a fixture deep into the tournament, but when they lost their leading scorer and assist leader in Kalin Lucas, no one expected them to be here either. There is a huge coaching experience edge to Michigan State here as Coach Izzo has led the Spartans to a 26-11 ATS mark in NCAA tournament action over the last 11 years, and has been 5-1 ATS as a dog. The Bulldogs are young and talented, but this is a brand new experience at the Final Four, so the experience factor should be the big player here. I'll go with Michigan State.