A huge showdown in the Italian Serie A League between the two best teams. AS Roma is in first place by one point but injuries are piling up with midfielder Nicolò Zaniolo, forward Pedro Rodríguez, and left-backs Davide Santon and Riccardo Calafiori out, while goalkeeper Antonio Mirante is rated doubtful. Visiting Inter Milan is healthy, outscoring league foes 41-21 with the top offense. Their +20 goal differential is also No. 1. Inter Milan is on an 8-1-1 run beating opponents 24-10 and is unbeaten in the last six meetings with AS Roma tallying 9 goals. Play Inter Milan on the moneyline.
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