Chicago at Houston

Chicago has lost two straight and leadoff hitter Dexter Fowler is in an 0-for-19 slump, which is problematical because the only time the Cubs struggled this season was when he was on the disabled list. This will also be the first time since 2008 that Jon Lester will face Houston. Joe Musgrove will make his seventh start this season and he has done his best work at home where he has a 0.54 ERA while allowing just a run and nine hits in 16 2/3 innings. The Cubs will be facing the right-hander for the first time. Chicago has lost Lester's last five road games against winning teams and the Astros have won 26 of their last 37 interleague games and 13 of their last 19 overall. Houston has won six of their last eight home games against the Cubs. Take the home underdog Astros.