Detroit at Buffalo

Matthew Stafford, who just signed a huge contract extension, won't play in this matchup. Brad Kaaya figures to get most of the playing time for the Lions, who have looked good so far in preseason in winning their first two games before losing 30-28 to the Patriots last week. Detroit racked up 417 yards of offense, including 118 rushing yards on 29 carries, including 60 yards on 13 carries by Ameer Abdullah, who was injured most of last season. Buffalo is looking for a quarterback as Tyrod Taylor and TJ Yates are in the concussion protocol. The Bills added free agent QB Keith Wenning on Monday and Nate Peterman is the only other quarterback available and he is expected to start. Detroit has won and covered the final preseason game the last two years and both were against Buffalo, including a 31-0 whitewash last season. The Bills are 0-3 while scoring a total of only 35 points and they are 0-9 ATS in Game Four the last nine years of preseason, while Detroit is 9-0 ATS in the same situation. Back the Lions.