Arizona at Los Angeles

Arizona is quietly on a 5-2-1 ATS run but is a huge dog here. The Cardinals have also covered four of five on the road against teams with winning home records. They've lost to the Bears and Seahawks by a combined five points, plus covered their only game as a double-digit dog, losing 26-14 at Kansas City as a +16-point puppy. NFL road teams that score between 14.5 and 18 points per game against an average defensive team allowing 18-23 ppg are 84-46 ATS after a loss by six or fewer points. This is a sandwich spot for the L.A. Chargers, facing a weak NFC team sandwiched around games against AFC teams, division rival Denver (23-22 loss last week) and at Pittsburgh next week. The Chargers are 4-9-1 ATS following a straight-up loss, plus 4-10 ATS after getting 350+ total yards in their previous game. And NFL favorites of 10.5+ that win 60-75% of their games are 43-79 ATS after covering the spread in two of their last three contests. Play Arizona.