NFL Football Matchups & Computer Predictions

Week 11: November 21, 2021 @ 01:00pm

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Indianapolis Colts at Buffalo Bills


COMPUTER PREDICTIONS STRAIGHT-UP
TEAM SCORE PERCENTAGE TO WIN GAME
Indianapolis Colts 21.134
28%
Buffalo Bills 28.066
72%
COMPUTER PREDICTIONS AGAINST THE SPREAD
TEAM SPREAD TOTAL
Indianapolis Colts +7.0 49.5
Buffalo Bills -7.0 49.5 U
PUBLIC CONSENSUS
TEAM SPREAD TOTAL
BETS PERCENTAGE BETS PERCENTAGE
Indianapolis Colts 1063 
57%
O 562 
48%
Buffalo Bills 791 
43% 
U 603 
52% 

Note: These are computer-derived matchups and do NOT represent my official picks. In order to make final picks, there is much more analysis required (injuries, trends, situations and other technical analysis). If you want my full analysis, detailed write-ups, and official picks, be sure to get my email newsletter.